IronQ Keep · Free Muscle Loss Check
On Ozempic, Wegovy, Mounjaro or Zepbound, a large share of the weight that comes off can be muscle. Answer five questions and see an estimate of how much of yours it may be, and what to do about it.
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In the main trials, about 39% of the weight lost on semaglutide (Ozempic, Wegovy) and about 25% on tirzepatide (Mounjaro, Zepbound) was lean tissue, measured by DXA scan. Lean tissue includes water as well as muscle, so muscle alone is less than that. How much you lose depends mostly on two things you control: whether you lift weights and how much protein you eat.
Lift weights two or three times a week, hard enough that the last two reps of each set are a struggle, and eat roughly 1.2 to 1.6 g of protein per kilogram of body weight a day. Then check it: if the weights you can lift keep falling while the scale drops, you are losing muscle along with fat.
A common target is 1.2 to 1.6 g per kilogram of body weight a day, which is about 110 to 145 g for someone weighing 200 lb. Appetite drops on these medications, so most people fall short without planning for it. Put protein first on the plate and use a shake when meals are small.
Studies of people who stop find that much of the weight tends to come back, and without training it can come back as more fat than muscle. Keeping up strength training through and after stopping is the best protection. IronQ Keep carries on after the last dose with a weight guardrail and the same strength checks.
Not directly. Only a scan measures muscle. What an app can measure is strength on the same machines week after week, which falls early when muscle is being lost. That is the signal IronQ Keep watches, and it tells you to get a DEXA scan when the trend says you should.